Sunday, February 14, 2010

Find a protien using PDB explorer- describe your protien, icluding what disease state of other real-world applictation it has.

The protein I chose was MOG or myelin oligodendrocyte glycoprotien which helps with the myelination of nerves and is believed to be involved in the disease multiple sclerosis . When observing the structure under the different views given one can see that the difference when looking at the backbone view and the all atoms view that the backbone picture does not show the R groups while they are shown in the all atoms form. The module allows you to examine the secondary structures were one can see alpha helices and beta pleated sheets. From looking at this protein I was able to see the structure of the molecule in 3D which is very helpful in determining structures and different bonds. This is all very useful because with the general structure of a protein given one can determine the proteins overall function and importance to the organism. Also one would be able to figure out how to possible make this molecule based on its overall structure.

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