Sunday, February 14, 2010

Find a protien using PDB explorer- describe your protien, icluding what disease state of other real-world applictation it has.

The protein I chose was MOG or myelin oligodendrocyte glycoprotien which helps with the myelination of nerves and is believed to be involved in the disease multiple sclerosis . When observing the structure under the different views given one can see that the difference when looking at the backbone view and the all atoms view that the backbone picture does not show the R groups while they are shown in the all atoms form. The module allows you to examine the secondary structures were one can see alpha helices and beta pleated sheets. From looking at this protein I was able to see the structure of the molecule in 3D which is very helpful in determining structures and different bonds. This is all very useful because with the general structure of a protein given one can determine the proteins overall function and importance to the organism. Also one would be able to figure out how to possible make this molecule based on its overall structure.

What is biochemistry, and how does it differ from the feilds of genetics,biology,chemistry, and molecular biology?

The science of biochemistry is the study of the chemical processes that take place in living organisms and the structures and functions of the biomolecules that are involved in these processes. Other fields such as chemistry, biology, and genetics discuss many of the topics touched upon in biochemistry but what makes it different is that biochemstry focuses on the monomers and polymers that make up the main molecules that biochemist focus on which are lipids, carbohydrates, nucleic acids, and protiens. It is the structure and propeties of these molecules that are the main focus of biochemists and how they function in living organisms.